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Diabetes a Global Challenge Answer
Week- 1: Epidemiology of Diabetes
1.
Question 1
How is the trend in occurrence of diabetes worldwide?
1 point
- Increasing
- Decreasing
- Stable
2.
Question 2
How is diabetes defined?
1 point
- A disease in which insulin works too effectively
- A disease in which glucose is excreted with the urine
- A disease in which the pancreas secretes no or too little insulin
3.
Question 3
What is the difference between type 1 and type 2 diabetes?
1 point
- Type 1 diabetes occurs only among children and type 2 only among adults
- In Type 1 diabetes, the pancreas produces no insulin, whereas in type 2 diabetes, the insulin produced does not work adequately
- Type 2 diabetes follows after some years with type 1 diabetes
4.
Question 4
How many different types of diabetes are there?
1 point
- Three main types and multiple more rare subtypes
- Two, type 1 and type 2 diabetes
- Three, type 1, type 2 and type 3 diabetes
5.
Question 5
Which region of the world is most severely affected by diabetes?
1 point
- Europe and Russia
- The Middle East and the Far East
- North, Central and South America
6.
Question 6
How is the age distribution at onset of type 2 diabetes?
1 point
- Type 2 diabetes patients get the disease shortly before they die from other diseases
- Type 2 diabetes is mainly emerging in late adulthood
- Type 2 diabetes emerges mainly during childhood and young adulthood
7.
Question 7
How can the global epidemic of diabetes lead to a public health crisis?
1 point
- Not enough medicine is produced to supply all the diabetic patients with what they need
- Nothing can be done about it
- The diabetic patients demand a medical care that many countries cannot afford to provide
8.
Question 8
What is impaired glucose tolerance?
1 point
- Glucose in the blood has been chemically modified and therefore cannot be tolerated
- Intake of glucose cannot be tolerated and leads to sickness
- Even though the pancreas secretes more insulin, it cannot keep the glucose levels down to normal levels
9.
Question 9
How is overweight affecting risk of diabetes?
1 point
- Increases the risk
- Decreases the risk
- Does not affect the risk
Week- 2: Obesity and Prevention of Diabetes
1.
Question 1
How much physical activity do major health agencies recommend for adults?
1 point
- At least 75 minutes of moderate-intensity or at least 35 minutes of vigorous-intensity aerobic physical activity per week – or a combination. Additionally, muscle-strengthening activities should be performed on 2 or more days a week.
- At least 300 minutes of moderate-intensity or at least 150 minutes of vigorous-intensity aerobic physical activity per week – or a combination. Additionally, muscle-strengthening activities should be performed on 4 or more days a week.
- At least 150 minutes of moderate-intensity or at least 75 minutes of vigorous-intensity aerobic physical activity per month – or a combination. Additionally, muscle-strengthening activities should be performed on 2 or more days a month.
- At least 150 minutes of moderate-intensity or at least 75 minutes of vigorous-intensity aerobic physical activity per week – or a combination. Additionally, muscle-strengthening activities should be performed on 2 or more days a week.
2.
Question 2
Compared to adults, major health agencies recommend children to be…
1 point
- … more physically active
- … less physically active
- … as physically active
3.
Question 3
The ‘state-of-the-art’ test for assessment of physical fitness is by…
1 point
- … heart rate monitoring
- … an activity questionnaire
- … quantification of maximal oxygen uptake by indirect calorimetry during a biking or running test to exhaustion
- … the doubly-labelled water method
4.
Question 4
Health benefits of being physically active include…
1 point
- … a decrease in insulin sensitivity and a higher heart stroke volume
- … decreases in plasma HDL-cholesterol and triglyceride
- … an increase in insulin sensitivity and a decrease in blood pressure
- … stronger tendons and softer skin
5.
Question 5
The influence of physical training on energy balance is more complicated than previously thought as…
1 point
- … compensatory mechanisms might come into play
- … seasonal changes affect both physical training and energy balance
- … smoking is increased by physical training
- … caffeine intake is reduced by physical training
6.
Question 6
Approximately 50 kcal are expended by…
1 point
- … playing with the children for two hours
- … a 60-minute workout in the fitness center
- … sleeping on the couch for 8 hours
- … a 10-minute walk during the lunch break
7.
Question 7
Metabolic health benefits of endurance training include…
1 point
- … an increase in HOMA-IR
- … an increase in waist circumference
- … an increase in peripheral insulin sensitivity
- … a decrease in HDL-cholesterol
8.
Question 8
People with diabetes and those at risk for diabetes…
1 point
- … cannot improve glycemic control by physical exercise
- … should abstain from physical activity
- … show decreases in peripheral insulin sensitivity after endurance training
- … should be physically active on a regular basis
Week- 3: Physiological Regulation of Plasma Glucose
1.
Question 1
What is the range of normal plasma concentrations?
1 point
- 3-12 mmol/l
- 5-7 mmol/l
- 4-10 mmol/l
2.
Question 2
Which is the correct statement? The glucose pool is:
1 point
- Extracellular volume multiplied the by plasma glucose concentration
- Intracellular volume multiplied by the plasma glucose concentration
- Total body water multiplied by the plasma glucose concentration
3.
Question 3
Which statement is false?
1 point
- glycerol may be converted into glucose
- Amino acids may be converted into glucose
- Lipids may be converted into glucose
4.
Question 4
Which is the correct statement? How can beta cells sense extracellular glucose concentrations?
1 point
- Because they express the glucose transporter GLUT-4
- Because intracellular glucose is converted to ketone bodies
- Because of the high Km of glucokinase
5.
Question 5
Which statement is false?: Insulin secretion is stimulated by…
1 point
- Arginine
- Sympathetic nerves
- Parasympathetic nerves
6.
Question 6
Which statement is false?
1 point
- The incretin effect is responsible for up to 70 % of the postprandial insulin secretion
- The incretin effect is responsible for keeping up insulin secretion in type 2 diabetes
- The incretin effect keeps post prandial glucose excursions low regardless of the carbohydrate load
7.
Question 7
Which statement is correct? In the liver, insulin…
1 point
- stimulates glycogenolysis
- Stimulates glycolysis
- Stimulates gluconeogenesis
8.
Question 8
Which statement is correct: Glucagon stimulates…
1 point
- glycogenesis
- glycolysis
- gluconeogenesis
9.
Question 9
Which is the correct statement? The limiting factor for prevention of deadly hypoglycaemia during prolonged fasting is:
1 point
- Cortisol-stimulated provision of gluconeogenic amino acids
- Glucose formation from ketone bodies
- Glucagon-stimulation of gluconeogenesis
10.
Question 10
Which is the false statement? During exercise plasma glucose does not fall very much because:
1 point
- Glycogenolysis in the muscles keeps it up
- Insulin secretion is inhibited
- Gluconeogenesis from lactate is increased
Week- 4: The Incretins
1.
Question 1
What is the name of the two incretin hormones?
1 point
- GLP-1 and GIP
- GLP-1 and oxyntomodulin
- GLP-1 and PYY
- Glucagon and GLP-1
2.
Question 2
Where is the incretin hormones secreted from?
1 point
- The brain
- The skin
- The gut
- The hair
3.
Question 3
What is the name of the cell type secreting the incretin hormones?
1 point
- Goblet cell
- Enterocyte
- Enteroendocrine
4.
Question 4
GLP-1 is derived from the prohormone called
1 point
- Glucagon
- Progip
- Proglp-1
- Proglucagon
5.
Question 5
Proconvertase 1/3 is responsible for the differential splicing of proglucagon to GLP-1 in the pancreas and not in the gut?
1 point
- Yes
- No
6.
Question 6
Where is GLP-1 primarily degraded?
1 point
- In the brain
- The capillaries draining the gut
- The capillaries of the gut and the liver
- The blood
7.
Question 7
GLP-1 affects
1 point
- Glucose regulation
- Appetite regulation
- Gastric emptying
- All of the options
8.
Question 8
GLP-1 responses are often impaired in T2D subjects?
1 point
- Yes
- No
9.
Question 9
Why are GLP-1 receptor agonists used as therapy in type 2 diabetes?
1 point
- Because GLP-1 inhibits glucagon secretion
- Because GLP-1 inhibits appetite
- All of the options
- Because GLP-1 stimulate glucose induced insulin secretion
10.
Question 10
Inhibition of the DPP-4 enzyme can be used as therapy of type 2 diabetes?
1 point
- Yes
- No
11.
Question 11
GLP-1 receptor agonists are administered
1 point
- Intravenously
- Orally
- Subcutaneously
- Rectally
12.
Question 12
How many per cent of subjects can skip their diabetes medication for their type 2 diabetes after gastric bypass surgery?
1 point
- 60
- 20
- 100
- 40
- 10
- 80
- 30
13.
Question 13
Which factors may be important for the remission of type 2 diabetes after gastric bypass
1 point
- Malabsorption of lipids
- Cytokines
- Malabsorption of carbohydrates
- Gut hormones
14.
Question 14
Is the release of gut hormones (e.g. GLP-1, PYY and Oxyntomodulin) increased after gastric bypass?
1 point
- No
- It has not been investigated
- Yes
15.
Question 15
What happens to insulin secretion if gastric bypass subjects receive a GLP-1Receptor antagonist during a meal challenge?
1 point
- The insulin secretion is increased
- The insulin secretion does not change
- The insulin secretion is diminished
Week- 5: Clinical manifestation of Diabetes and treatment
1.
Question 1
Choose the correct answer:
1 point
- The diabetes epidemics occur as a result of a true increased incidence of the disease in all countries.
- Lowering of diagnostic criteria for T2D has contributed to the increased incidence of the disease.
- The largest increase in future T2D incidence is expected to take place in affluent Western societies.
2.
Question 2
Choose the correct answer:
1 point
- The 2 hours cut-off level for the T2D diagnosis based on an oral glucose tolerance test was based on association studies showing increased risk of microvascular complications with levels above the diagnostic threshold.
- Patients with T2D do not have increased risk of cardiovascular disease after correction for the ambient plasma glucose levels.
- Lowering of the cut-off criteria for fasting plasma glucose in T2D diagnosis is based on randomized trials providing conclusive evidence that intensive glucose control lower cardiovascular mortality.
3.
Question 3
Choose the correct answer:
1 point
- The idea of T2D being a ”category error” reflect inappropriate knowledge about the origin and underlying pathophysiological mechanisms in T2D.
- The idea of T2D as a ”category error” reflect that it resemble T1D more than generally recognized.
- The idea of T2D being a ”category error” reflects inappropriate attention to the known increased risk of cardiovascular complications associated with the disease.
4.
Question 4
Choose the correct answer:
1 point
- The association between T2D, hypertension and dyslipidaemia may be explained by common factors occurring in foetal life influencing the risk of all of these phenotypes
- The association between T2D, hypertension and dyslipidaemia is based on a common genetic origin illustrated by clustering of these states of disease in families.
- The association between T2D and cancer is due to glucose lowering agents including insulin causing cancer.
5.
Question 5
Choose the correct answer:
1 point
- All patients with T2D benefit to the same extent from intensive versus conventional glucose lowering treatment.
- Individualized treatment of patients with T2D means that those who are expected to benefit most from the different treatment modalities will get increased access to this from health care providers.
- Individualized treatment of patients with T2D will result in increased health care expenses.
6.
Question 6
Choose the correct answer:
1 point
- Intensive glucose lowering treatment does not reduce cardiovascular mortality in T2D.
- Multifactorial intervention does not reduce mortality from cardiovascular disease in T2D.
- The legacy effect means that intensive glucose lowering treatment initiated immediately after the T2D diagnosis will ensure that the patient does not develop micro- or macro vascular complications.
7.
Question 7
Choose the correct answer:
1 point
- All patients with T2D exhibit absolute defects of multiple organs including the liver, muscle, adipose tissue, the pancreatic beta cell, as well as gut incretin hormone functions.
- Impaired left ventricular heart function increase the risk of developing T2D.
- Genetic factors do not influence the risk of developing T2D.
8.
Question 8
Choose the correct answer:
1 point
- A DXA scanning provides accurate information about the amount of intra-abdominal (visceral) fat.
- Lack of expandability of the subcutaneous adipose tissue may impact adversely on glucose homeostasis due to fat accumulation and lipotoxicity in muscle, fat and the pancreatic beta cell.
- Neuro-cognitive dysfunctions in T2D including depression occur solely as a result of the elevated plasma glucose level.
9.
Question 9
Choose the correct answer:
1 point
- Hales and Barker were the first scientists who proposed that adverse early life conditions increases the risk of developing adult non-communicable cardiometabolic diseases.
- Low birth weight is to a large extent explained by known T2D susceptibility genes causing low pancreatic insulin secretion and subsequently reduced growth in foetal life.
- The ”thrifty phenotype hypothesis” provides a potential explanation for the multiple organ dysfunctions in T2D.
10.
Question 10
Choose the correct answer:
1 point
- Lifestyle interventions improving diet and physical activity habits provide sustainable prevention of T2D as well as its micro- and macro vascular complications.
- None of the currently used glucose lowering agents reduces the risk of diabetic vascular complications beyond their glucose lowering effects
- Metformin and GLP-1 agonists are the only glucose lowering drugs which conclusively have been shown to reduce cardiovascular mortality in T2D.
Week- 6: Inflammatory Beta-cell Destruction in Diabetes
1.
Question 1
What is the cause of diabetes?
•
•
•
1 point
- Most diabetes is due to mutations in the insulin signalling pathway causing insulin resistance
- Most diabetes is caused by reduced tubular glucose reabsorption causing glucosuria
- Most diabetes is due to relative or absolute insulin deficiency
2.
Question 2
What is the reason that insulin-resistant people progress from normal glucose tolerance to impaired glucose tolerance and diabetes?
1 point
- Because of increased glucagon secretion from the pancreatic islets
- Because of increased sucrose absorption from the gut
- Because insulin secretion fails to compensate for insulin resistance
3.
Question 3
Insulin secretion in diabetes is…
1 point
- reduced only because of impaired beta-cell function
- increased because of increased beta-cell mass
- reduced because of impaired beta-cell function and mass
4.
Question 4
What are the immune-cells involved in beta-cell killing in T1 diabetes?
1 point
- B-lymphocytes and Th2 cells
- Macrophages and cytotoxic T-cells
- Dendritic cells and Th2 cells
5.
Question 5
How are macrophages believed to kill beta-cells in diabetes?
1 point
- By direct cell-to-cell contact (‘a deadly kiss’)
- By recognition of danger-associated molecular beta-cell patterns causing membrane perforation
- By secretion of inflammatory mediators
6.
Question 6
How are T-cells believed to kill beta-cells in T1 diabetes?
1 point
- By the release of bradykinins, histamine and prostaglandins
- By the secretion of nitric oxide radicals
- By the Fas/FasL or perforin/granzyme pathway
7.
Question 7
How do metabolic factors affect insulin sensitive tissues and beta-cells in T2 diabetes?
1 point
- By causing low-grade inflammation and gluco-lipotoxicity in the cells
- By causing vascular dysfunction, reduced blood flow and ischemia in the tissues
- By causing accumulation of glycogen and protein deposits in the cells
8.
Question 8
What is a common consequence of islet inflammation in T1 and T2 diabetes?
1 point
- Beta-cell necrosis
- Alpha cell apoptosis
- Beta-cell apoptosis
9.
Question 9
How do beta-cell sense inflammatory signals?
1 point
- By beta-adrenergic receptors
- By cytokine and Toll-like receptors
- By mitochondrial oxidation of the increased glucose levels
10.
Question 10
What are the perspectives for future antiinflammatory therapies in T1 diabetes?
1 point
- To combine T-cell inhibitors and activators of the innate immune system
- To combine T-cell activators and inhibitors of the innate immune system
- To combine T-cell inhibitors and inhibitors of the innate immune system
11.
Question 11
What are the perspectives for future antiinflammatory therapies in T2 diabetes?
1 point
- Antiinflammatory therapy given from birth in children at genetic risk for T2 diabetes
- Short courses of antiinflammatory therapy may break glucose-driven islet inflammation
- Long-term cytokine biologics as monotherapy from onset of T2 diabetes
Week- 7: Genetic Aspects of Diabetes
1.
Question 1
Type 2 diabetes is a complex disease with an important genetic component. The prevalence of type 2 diabetes in the adult European population is about 5-10%. What is the lifetime risk for the offspring for developing type 2 diabetes:
1 point
- 90-100%
- 5-10%
- 30-40%
2.
Question 2
Heritability measures the fraction of phenotype variability that can be attributed to genetic variation. What is the heritability of body mass index (BMI):
1 point
- 5-10%
- 10-20%
- >50%
3.
Question 3
The Human Genome Project has revealed the approximate number of protein coding genes in the human genome. That is:
1 point
- >100,000 genes
- About 5,000-10,000 genes
- About 20,000-25,000 genes
4.
Question 4
A 2 month old child is diagnosed with diabetes. The child has likely:
1 point
- Neonatal diabetes
- Type 1 diabetes
- Type 2 diabetes
5.
Question 5
Do we need to perform a genetic test in a 2 month old child diagnosed with diabetes:
1 point
- No, the diagnosis is most likely type 2 diabetes which could be treated with metformin
- Yes, a genetic test will often reveal the correct diagnosis and will allow for counseling and optimal treatment choices
- No, the diagnosis is most likely type 1 diabetes which should be treated with insulin
6.
Question 6
Maturity Onset Diabetes of the Young (MODY) is a common form of monogenic diabetes accounting for up to:
1 point
- 5-10% of all cases of diabetes
- 1-2% of all cases of diabetes
- >10% of all cases of diabetes
7.
Question 7
Children diagnosed with GCK-diabetes (MODY2) should be treated with:
1 point
- No treatment
- Metformin
- Sulphonylurea
8.
Question 8
Patients diagnosed with HNF1A-diabetes (MODY3) with elevated glucose levels should be offered treatment with:
1 point
- Sulphonylurea
- Metformin
- Insulin
9.
Question 9
Genome wide association studies have revealed a number of common variants which increases the risk of type 2 diabetes. How many type 2 diabetes risk variants have been reported:
1 point
- About 10
- About 20
- >50
10.
Question 10
Is it important to perform genetic testing for monogenic forms of diabetes in selected patient groups:
1 point
- Yes, testing makes the right diagnosis, helps counseling and can guide choice of treatment
- No, following present treatment guidelines are sufficient
- No, circulating biomarkers can be used to diagnose specific forms of diabetes which makes the right diagnosis, helps counseling and can guide choice of treatment
Week- 8: Translational Aspects
1.
Question 1
Translational
science is
1 point
- from
diabetes to treatment - from
bedside to lab bench - from lab bench to bedside
2.
Question 2
During an OGTT in subjects with mutations on their KCNQ1 receptor the consequence was
1 point
- Hyperglycemia
- Hypoglycemia
- Euglycemia
3.
Question 3
Patients with
mutation in their GIP receptor had
1 point
- Lower fracture risk
- higher fracture risk
- no difference
Week- 9: Development of antidiabetic agents
1.
Question 1
The response of GI hormones during a meal is
1 point
- The secretion of GI hormones e.g. GLP-1 is reduced
- No response
- The secretion of GI hormones e.g. GLP-1 is increased
2.
Question 2
Ghrelin levels increase during intake of a meal
1 point
- True
- False
- Nothing happens to ghrelin
3.
Question 3
The Gut microbiota may assist the conversion of carbohydrates (fibres) into
short chain fatty acids (SCFA)
1 point
- False
- True
4.
Question 4
Gut hormones may exert
1 point
- Paracrine functions
- All of the mentioned options
- Neuronal activation (e. g. sensory vagal afferents)
- Endocrine functions
5.
Question 5
What does residual capacity of the enteroendocrine cells means?
1 point
- That they have residual ATP
- That the enteroendocrine cells may still be able to release hormone upon additional stimulation by e.g. nutrients (a bigger meal )
- That more GLP-1 is being secreted
- Nothing, just an expression
6.
Question 6
Which of the following hormones may influence satiety in humans?
1 point
- PYY
- Ghrelin
- CCK
- GLP-1
- All of the mentioned options
7.
Question 7
The melanocortin receptor 4 is not associated with obesity?
1 point
- False
- We don’t know
- True
8.
Question 8
What is the meaning of the expression: the gut-brain axis?
1 point
- That activities in the gut may influence brain activities
- That it is the gut which controls our emotions?
- Nobody knows
- That the brain controls the gut
9.
Question 9
Which receptor(s) does Amferpramone block?
1 point
- DAT
- All of the mentioned
- NET
- SERT
10.
Question 10
What is the main effect of Orlistat?
1 point
- Inhibition of the pancreatic lipase
- Inhibition of NET
- Inhibition of adrenergic receptors
11.
Question 11
Can GLP-1 analogs been used in treatment of obesity?
1 point
- Yes, but the GLP-1 analogue need to be resistant to inactivation by DPP-4
- No
- Yes
12.
Question 12
Can mixture of more than one peptide be beneficial in treatment of obesity?
1 point
- No
- Yes, use of more than one peptide can be beneficial in treatment of obesity
13.
Question 13
Glucagon together with GLP-1 could be an important co-agonist in treatment of diabetes and obesity?
1 point
- True
- False
- Glucagon does not regulate satiety
- Maybe
Week- 10: Stem Cell Based Therapy of Diabetes
1.
Question 1
Diabetes late complications distinguish type 1 diabetes from type 2 diabetes.
1 point
- True
- No, it is the reverse
- No, both forms of diabetes can result in similar severe late complications.
2.
Question 2
Obese insulin-resistant people with normal blood-glucose levels have…
1 point
- … a reduced beta cell mass compared to weight-matched T2D patients
- … an unchanged beta cell mass compared to weight-matched T2D patients
- … a greater beta cell mass compared to weight-matched T2D patients
3.
Question 3
Why is a constant blood-glucose important? (multiple answers are allowed in this question)
1 point
- It secures constant energy to the brain
- It prevents many of the diabetes late complications to develop
- It allows you to effectively secrete glucose into the urine
4.
Question 4
Which symptom is considered amongst the worst when suffering from insulin-dependent diabetes?
1 point
- Normoglycemia
- Hypoglycemia
- Hyperglycemia
5.
Question 5
The “Edmonton protocol” (published in yr 2000) refers to (multiple answers are allowed in this question):
1 point
- Organ donor islet transplantation of T1D that effectively lead to strong reduction of recurrent hypoglycemic episodes
- Organ donor islet transplantation of T1D patients to reach a situation where need for insulin injections may be strongly reduced or not needed
- Whole pancreas transplantation to cure diabetes.
6.
Question 6
Circulating C-peptide levels in T1D patients indicate (multiple answers are allowed in this question):
1 point
- That they will have a greater probability to develop severe complications
- That patients still produce some endogenous insulin
- Presence of active, living beta cells that have not yet been destroyed by autoimmunity
7.
Question 7
What is the major mechanism used by our body to secure maintenance of adult stem cells (or tissue stem cells) throughout life?
1 point
- Asymmetrical cell division
- Symmetrical cell division
- Neo-formation
8.
Question 8
From which germ layer are the insulin producing pancreatic beta cells are derived?
1 point
- Endoderm
- Ectoderm
- Mesoderm
9.
Question 9
Encapsulation of therapeutic beta cells serve the following purpose(s) (multiple answers are allowed in this question):
1 point
- To protect against attack from the patient’s immune system
- Eliminates the need for anti-rejection therapy
- To shield the cells against oxidative stress
10.
Question 10
The pancreas is 98% exocrine and 2 % endocrine – what does it mean?
1 point
- The endo- and exocrine cells secrete their products into the blood stream
- The endocrine products are secreted into the blood stream while the exocrine products are secreted via the duct to the intestine
- The endo- and exocrine cells secrete their products via the ductal system to the intestine
Week- 11: Exercise – how does it work?
1.
Question 1
What kind of fat distribution is most dangerous in relation to the development of Type 2 Diabetes?
1 point
![Diabetes a Global Challenge Coursera Quiz Answer [💯Correct Answer] 2 cx 9 K23 QEeakk Arq5 q3 Ow cb6e86913f8e47a7411fbebb73b0f930 abdominal fat](https://i.ibb.co/V3VBHGG/cx-9-K23-QEeakk-Arq5-q3-Ow-cb6e86913f8e47a7411fbebb73b0f930-abdominal-fat.png)
2.
Question 2
Melissa has been severely injured in an accident and spends 3 weeks in bed to recover. What is the impact on her physical work capacity if you measure in years of ageing?
1 point
- Equivalent to 10 years of ageing
- Equivalent to 20 years of ageing
- Equivalent to 30 years of ageing
- Equivalent to 40 years of ageing
3.
Question 3
Ann, Beatrice and Cathrine are sisters. Who is most at risk of developing type 2 diabetes?
1 point
Ann
Age: 51
Weight: 74
BMI: 29
Physical activity: takes bus and train to work, walks a lot at work, plays tennis once a week.
Beatrice
Age: 54
Weight: 79
BMI: 27
Physical activity: drives to work, no regular exercise
Catherine
Age: 55
Weight: 80
BMI: 31
Physical activity: bikes to work, does yoga twice a week.
4.
Question 4
What are the effects of the myokines that are secreted from skeletal muscles during exercise?
1 point
- They provoke an inflammatory state in some organs.
- They have no effect on organs, they help build muscle tissue.
- They have beneficial effects on several organs.
5.
Question 5
Which of the following proteins are secreted from an exercising leg?
1 point
- IL-4
- Glucagon
- Adiponectin
- Follistatin
- GLP-1
- IL-7
- IL-6
6.
Question 6
How may exercise prevent tumour growth?
1 point
- Exercise increases the number of immune cells and directs them towards the tumour.
- Exercise does not prevent tumour growth
- The myokines secreted in respons to exercise directly attacks cancer cells.
7.
Question 7
What are the effects of inflammation?
1 point
- Inflammation enables us to fight infections.
- Inflammation increases levels of pro-inflammatory cytokines.
- Inflammation increases levels of myokines.
- There are no effects of inflammation.
8.
Question 8
Does the location of fat affect systemic inflammation?
1 point
- Yes, because the location of fat affects the secretion of myokines.
- No, fat affects inflammation independent of location.
- Yes, because (in particular) visceral fat induces low-grade inflammation.
9.
Question 9
Why is exercise beneficial for a wide range of chronic illnesses like Dementia, Cancer, Depression and Type 2 Diabetes?
1 point
- Exercise reduces systemic inflammation and provides proper navigation for immune cells to find cancerous cells.
- Exercise is not beneficial for chronic illnesses.
- Exercise only have acute effects on our health and not long-term effects.
- I understand that submitting another’s work as my own can result in zero credit for this as
Week- 11
Peer-graded Assignment: Peer graded assignment
Conclusion
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